A negative BRCA genetic test result is not the all-clear most people treat it as.

Natalie Samson is a board-certified integrative genetic counselor and the founder of Golden Genetics, where she pairs medical diagnostic testing with functional genomics to build personalized action plans.

My own counselor recently told me the panel I did has expanded from 13 genes to roughly 270, which means a result from years ago may not tell the whole story anymore.

Natalie breaks down what genetic testing actually measures and how ancestry kits differ from medical panels at the technology level. Family history patterns matter as much as the test itself. The vertical pattern she looks for across generations signals that a genetic mutation may be getting passed down.

A positive result is not a diagnosis. Insurance covers more than most people realize, and some cancer panels through her practice cost under $100.

Her four Ps framework ties the whole conversation together: proactive, preventative, personalized, and precision care.

If cancer, heart disease, or Alzheimer’s runs in your family, or you’ve been chasing symptoms with no answers, this episode gives you a clearer picture of what testing can do and when it’s worth pursuing.



You’ll learn:

[0:00] Introduction

[4:45] What we’re actually testing when we test genes

[8:38] An MTHFR variant is not the same as a BRCA mutation

[14:27] My cancer was linked to glyphosate, not genes

[17:14] Natalie’s father’s stage four cancer and the testing he was never offered

[20:44] Why a negative BRCA result can give false reassurance

[26:22] Cancers diagnosed under 50 and what they signal about genetic risk

[31:41] Tumor sequencing and how it targets treatment

[38:22] Testing positive for BRCA does not mean you will get cancer

[44:35] Nutrigenomics and the cellular pathways it reads

[54:14] Cutting 40 influencer supplements down to what works

[1:00:01] Who should especially consider a genetic counselor

Resources mentioned:

Quest Diagnostics |Website

LabCorp |Website

Dr. William Li |Website

Angelina Jolie, inherited breast cancer and the BRCA1 gene by Scowcroft, H. |Article

Find more from Natalie:

Natalie Samson | Instagram |4P Framework Quiz

Golden Genetics |Website |Instagram

Book a free Logistics call with Natalie here.

Find more from Michelle:

Revival Health & Wellness | Instagram | Facebook | Website

Cancer Proof Living | YouTube

Michelle Patidar | LinkedIn